Adrenaline Nebuliser Indication

Alert Adrenaline 1:1000 strength should be used for nebulisation. Indication Management of post -extubation stridor [evidence for effectiveness is not clear]. [1-4], adrenaline, or IPPB over simple nebulisation. (LOE II, GOR B) Safety: Nebulised adrenaline is associated with increased heart rate and blood pressure. [2, 8] Pharmacokinetics: Not reported for nebuliser use in newborns or children. No difference in plasma adrenaline concentrations in asymptomatic children with history of anaphylaxis, ? 1:1,000 (1 mg/mL) adrenaline (epinephrine) presentation should be used for all nebuliser administration. ? 1:10,000 (100 microg/1 mL ) or a 1 : 100,000 (10 microg/1 mL ) adrenaline (epinephrine) preparation should be used for all low dose IM/IV injections. Ensure all syringes are appropriately labelled.

Evidence shows that nebulization with 3 to 5 ml of adrenaline (1:1000) is a safe therapy, with minor side-effects, for children with acute inflammatory airway obstruction. [The safety of nebulization with 3 to 5 ml of adrenaline (1:1000) in children: an evidence based review] J Pediatr (Rio J).

[The safety of nebulization with 3 to 5 ml of adrenaline.

Appendix 16. Epinephrine nebulization - Management of a.

[The safety of nebulization with 3 to 5 ml of adrenaline.

ADRENALINE/EPINEPHRINE | Drug | BNF content published by NICE, 10/04/2021 ÿú Indication : Anaphylaxis Acute asthmatic attack Asystole/Pulseless arrest Symptomatic bradycardia Croup Contraindications : Epinephrine is contraindicated in patients with known hypersensitivity to sympathomimetic amines, angle closure glaucoma, and in nonanaphylactic shock.;"